VU0405601
CAS No. : 712325-30-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $283 | In-stock |
| 10mg | $452 | In-stock |
| 25mg | $814 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-116759 |
| M.Wt: | 357.20 |
| Formula: | C17H13BrN2O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
VU0405601 is a potent KV11.1 channel activator. VU0405601 protects cardiac tissue from Dofetilide (HY-B0232)-induced ventricular tachycardia[1][2].
IC50 & Target:KV11.1[1]
In Vitro:VU0405601 (5 µM; pretreated for 30 min before 100 nm Dofetilide) protects cardiac tissue from dofetilide (HY-B0232)-induced ventricular tachycardia[2].
VU0405601 (50 µM) can be used as a hERG agonist and increases test pulse and tail currents, increases the IC50 of Dofetilide from 38.7 to 76.3 nm[2].
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