Sulfobromophthalein (disodium salt)
CAS No. : 71-67-0
(Synonyms: Bromosulfophthalein (disodium salt))
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| Cat. No. : | HY-D0217 |
| M.Wt: | 838.00 |
| Formula: | C20H8Br4Na2O10S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Sulfobromophthalein (Bromosulfophthalein) disodium salt is an organic anion dye used in the study of a variety of membrane carriers expressed in animal tissues and involved in transport of drugs and metabolites[1].
In Vitro: Sulfobromophthalein disodium salt is a synthetic dye introduced in 1925 as a clinical tool aiming at the assessment of the liver function[1].
Sulfobromophthalein (BSP) is a pH indicator dye, featured by fast (17), protondependent quinoidal–phenolic tautomerism (pK = 8.5) [1].
Bromosulfalein has been commonly used as both a substrate and inhibitor of organic anionic transporting polypeptide 1B1 (OATP1B1), OATP1B3, OATP1A2, and OATP2B1, as well as multidrug resistance protein 2 (MDR2) [2].
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