XL 999
CAS No. : 705946-27-6
(Synonyms: Tyrosine kinase-IN-1)
| Size | Price | Stock |
|---|---|---|
| 5mg | $70 | In-stock |
| 10mg | $120 | In-stock |
| 25mg | $240 | In-stock |
| 50mg | $370 | In-stock |
| 100mg | $520 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-100315 |
| M.Wt: | 445.53 |
| Formula: | C26H28FN5O |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
XL999 is a multi-target tyrosine kinase inhibitor. XL999 has IC50 values for KDR, Flt-1, FGFR1 and PDGFRα of 4 nM, 20 nM, 4 nM and 2 nM, respectively. XL999 can be used in the research of cancer[1]. IC50 & Target:IC50: 4 nM (KDR), 20 nM (Flt-1), 4 nM (FGFR1), 2 nM (PDGFRα)[1] In Vivo:XL 999 shows a reasonable PK profile (AUC(0–∞)=1.9, t1/2=4.6 h). It has a favorable oral bioavailability (F=63%) in rats[1].
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