Avobenzone
CAS No. : 70356-09-1
| Size | Price | Stock |
|---|---|---|
| 25g | $8 | In-stock |
| 100g | $21 | In-stock |
| 500g | $102 | In-stock |
| 1000g | $191 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-B0316 |
| M.Wt: | 310.39 |
| Formula: | C20H22O3 |
| Purity: | >98 % |
| Solubility: | H2O : ≥ mg/mL;DMSO : ≥ 50 mg/mL |
Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist[1][2].
In Vitro: Avobenzone (EC50=14.1 μM) significantly promots adipogenesis in hBM-MSCs as its positive control obesogenic chemicals. Avobenzone (10 μM) significantly up-regulates mRNA levels of PPARγ during adipogenesis in hBM-MSCs[2].
Avobenzone (1-50 μM; 48 hours) inhibits proliferative activities of human trophoblast cells[3].
Avobenzone (1-50 μM; 48 hours) induces apoptosis in HTR8/SVneo cells[3].
Avobenzone only shows weak ERa agonism and weak AR antagonism[4].
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