Pertussis Toxin


CAS No. : 70323-44-3

70323-44-3
Price and Availability of CAS No. : 70323-44-3
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Cat. No. : HY-112779
M.Wt: 1000.00
Formula: N/A
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 70323-44-3 :

Pertussis Toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. Pertussis Toxin inhibits G protein-coupled receptor (GPR) signaling through Gi proteins[1][2][3]. In Vitro: Pertussis toxin is a secreted protein exotoxin and an important virulence factor produced exclusively by B. pertussis[1].
Pertussis toxin (PTX; 100 ng/ml; 12 h) completely suppresses the increase in G protein-coupled receptor kinase 2 (GRK2)-dependent migration in HeLa cells[2].

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