| Size | Price | Stock |
|---|---|---|
| 1g | $37 | In-stock |
| 5g | $129 | In-stock |
| 10g | $233 | In-stock |
| 25g | $453 | In-stock |
| 50 g | Get quote | |
| 100 g | Get quote | |
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| Cat. No. : | HY-76737 |
| M.Wt: | 204.65 |
| Formula: | C12H9ClO |
| Purity: | >98 % |
| Solubility: |
4-Chlorodiphenyl ether is an estrogen-mimicking active compound. 4-Chlorodiphenyl ether maintains the survival of endometriotic cysts and exhibits estrogenic activity associated with the growth of endometriotic implants. 4-Chlorodiphenyl ether can be used in research related to endometriosis[1].
In Vivo:4-Chlorodiphenyl ether (10-150 mg/kg/day; subcutaneous injection; daily administration for 28 consecutive days) dose-dependently increases the survival rate of endometriotic cysts in ovariectomized B6C3F1 mice. The cyst survival rate reaches 60% in the 150 mg/kg/day group, which is significantly higher than that in the vehicle control group. In addition, the highest dose alters the activity of hepatic microsomal enzymes[1].
4-Chlorodiphenyl ether (68 nmol/kg; intravenous injection; single administration) is rapidly cleared from the blood of rays, mainly accumulates in the liver with slow elimination, and has a total body clearance rate of 4.05 mL·min−1·kg−1[2].
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