Terazosin (hydrochloride dihydrate)


CAS No. : 70024-40-7

70024-40-7
Price and Availability of CAS No. : 70024-40-7
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Cat. No. : HY-B0371A
M.Wt: 459.92
Formula: C19H30ClN5O6
Purity: >98 %
Solubility: DMSO : 31.25 mg/mL (ultrasonic);H2O : 12.5 mg/mL (ultrasonic)
Introduction of 70024-40-7 :

Terazosin hydrochloride dihydrate is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist. Terazosin hydrochloride dihydrate works by relaxing blood vessels and the opening of the bladder. Terazosin hydrochloride dihydrate has the potential for benign prostatic hyperplasia (BPH) and high blood pressure treatment[1][2][3]. IC50 & Target: α1-adrenoceptor[1] In Vitro: Terazosin does not discriminate cloned α1-adrenoceptor subtypes transiently expressed in COS cells[1]. In Vivo: Terazosin can be used to promote stone discharge in treatment of ureteral stones. Terazosin is reportedly safe and effective in treatment of distal ureteral stones, especially stones >5 mm[3].

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