2-Fluoroadenine
CAS No. : 700-49-2
| Size | Price | Stock |
|---|---|---|
| 1g | $13 | In-stock |
| 5g | $50 | In-stock |
| 10g | $90 | In-stock |
| 25g | $204 | In-stock |
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| Cat. No. : | HY-W008469 |
| M.Wt: | 153.12 |
| Formula: | C5H4FN5 |
| Purity: | >98 % |
| Solubility: | DMSO : 20.83 mg/mL (ultrasonic;warming;heat to 80°C) |
2-Fluoroadenine is a toxic purine bases. 2-Fluoroadenine has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for researching anticancer[1].
IC50 & Target: DNA/RNA synthesis[1]
In Vitro: 2-Fluoroadenine (2 μM; 4 hours) inhibits CEM cell growth by targeting one or more enzymes involved in either RNA or protein synthesis[1].
2-Fluoroadenine (0-1000 μM; 96 hours) exhibits cytotoxicity in nonproliferating MRC-5 cells[1].
2-Fluoroadenine (0.22, 2.2 and 22 μM; 30 hours) inhibits protein, RNA, and DNA syntheses in Balb-3T3 cells incubated in serum-free medium[1].
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