L-Ornithine


CAS No. : 70-26-8

(Synonyms: (S)-2,5-Diaminopentanoic acid)

70-26-8
Price and Availability of CAS No. : 70-26-8
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1g $156 In-stock
5g $485 In-stock
25g $1321 In-stock
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Cat. No. : HY-B1352
M.Wt: 132.16
Formula: C5H12N2O2
Purity: >98 %
Solubility: DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C);H2O : 50 mg/mL (ultrasonic)
Introduction of 70-26-8 :

L-Ornithine ((S)-2,5-Diaminopentanoic acid) is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine shows nephroprotective[1][2]. In Vitro:L-Ornithine (0-10 mM) activates the CaSR in a concentration-dependent manner and exerts effects on Ca2+ signaling in HK-2 cells[2].
L-Ornithine (10 mM) activates TRPC channels mediated Ca2+ entry pathway in HK-2 cells[2].
L-Ornithine (100 or 300 μM; 24 h) shows the protection against ROS generation in HK-2 cells via ROCE pathway[2].
L-Ornithine (10 μM) can protect the ROS and oxidative damage in HK-2 cells exposed to H2O2[2].

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