RGH-5526
CAS No. : 69579-13-1
(Synonyms: GYKI-11679)
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| Cat. No. : | HY-100151 |
| M.Wt: | 335.40 |
| Formula: | C16H25N5O3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
RGH-5526 (GYKI-11679) is a new antihypertensive agent. In Vivo: RGH-5526 (GYKI-11679) is a new antihypertensive agent. Results show a sharp (61%) reduction in the hypothalamic Noradrenaline (NA) level 2 h after the administration of 10 mg/kg of RGH-5526, and this effect lasts for 4 to 6 h. It is demonstrated that RGH-5526 exerts a greater NA lowering effect in the hypothalamus than in the periphery. RGH-5526 does not influence the hypothalamic monoamine oxidase (MAO)-activity following prolonged treatment[1].
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