Harpagide


CAS No. : 6926-08-5

6926-08-5
Price and Availability of CAS No. : 6926-08-5
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Cat. No. : HY-N0397
M.Wt: 364.35
Formula: C15H24O10
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 6926-08-5 :

Harpagide is a class of iridoid glycoside isolated from Scrophularia ningpoensis and has antiparasitic activity, which exhibits good in vitro trypanocidal activities against African trypanosomes (T.b. rhodesiense) with an IC50 of 21 μg/mL. Harpagide exerts significant antileishmanial activity against L. donovani with an IC50 value of 2.0 μg/mL. Harpagide also possess significant anti-inflammatory activities[1][2]. In Vitro: Harpagide shows cytotoxic activity over 50% in a concentration of 90 μg/mL, Harpagide on the A431 and HeLa cell lines. The cytotoxic effect of Harpagide on the MCF7 cell line in a concentration of 90 μg/mL[3].

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