Moracin C
CAS No. : 69120-06-5
| Size | Price | Stock |
|---|---|---|
| 1mg | $107 | In-stock |
| 5mg | $321 | In-stock |
| 10mg | $541 | In-stock |
| 25mg | $944 | In-stock |
| 50mg | $1572 | In-stock |
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| Cat. No. : | HY-N3245 |
| M.Wt: | 310.35 |
| Formula: | C19H18O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Moracin C, a natural product, is an anti-inflammatory agent. Moracin C inhibits LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) release from cells[1].
In Vitro:Moracin C (1-50 μM, 24 h) inhibits LPS-activated reactive oxygen species (ROS) and nitric oxide (NO) release from RAW264.7 cells[1].
Moracin C (1-50 μM, 2 h) inhibits mRNA and protein expression of iNOS and COX-2 in RAW264.7 cells[1].
Moracin C (1-50 μM, 2 h) inhibits pro-inflammatory cytokine (IL-1β, IL-6 and TNF-α) productions in LPS-activated RAW 264.7 cells[1].
Moracin C (1-50 μM, 2 h) inhibits phosphorylation of p38, ERK and JNK in LPS-activated RAW 264.7 cells[1].
In Vivo:Moracin C (100 mg/kg, oral gavage, mice) was rapidly and well absorbed in the intestinal tract, and was highly distributed in the gastrointestinal tract, liver, kidneys, and lungs[2].
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