Carbazochrome


CAS No. : 69-81-8

69-81-8
Price and Availability of CAS No. : 69-81-8
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Cat. No. : HY-B1587
M.Wt: 236.23
Formula: C10H12N4O3
Purity: >98 %
Solubility: H2O : 5 mg/mL (ultrasonic;adjust pH to 12 with NaOH);DMSO : 4 mg/mL (ultrasonic;warming;heat to 60°C)
Introduction of 69-81-8 :

Carbazochrome is a capillary stabiliser and used for the research of haemorrhage. Carbazochrome is an antihemorrhagic agent[1]. In Vitro: Carbazochrome (0.1-10 µM) inhibits the Bradykinin induced and thrombin-induced formation of [3H]IP3 in a concentration-dependent manner[1]. Carbazochrome (0.1-1 µM), when included from 30 min before stimulation, significantly suppressed the enhancement of permeability induced by vasoactive substances[1]. In Vivo: Carbazochrome inhibits the severe pulmonary dysfunction induced by the intravenous injection of radiographic contrast media. Carbazochrome (1-10 mg/kg, i.v.) attenuates pulmonary dysfunction induced by a radiographic contrast medium in rats[2].

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