Ampicillin (sodium)


CAS No. : 69-52-3

(Synonyms: D-(-)-α-Aminobenzylpenicillin (sodium salt))

69-52-3
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Cat. No. : HY-B0522A
M.Wt: 371.38
Formula: C16H18N3NaO4S
Purity: >98 %
Solubility: H2O : ≥ 200 mg/mL
Introduction of 69-52-3 :

Ampicillin sodium (D-(-)-α-Aminobenzylpenicillin sodium salt) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria[1]. IC50 & Target:Bacterial[1] In Vitro:Ampicillin inhibits the growth of E. coli of swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin was 2.5 uG/mL[1]. In Vivo:Ampicillin is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig[1]. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood[2]. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia[3].

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