Liothyronine
CAS No. : 6893-02-3
(Synonyms: Triiodothyronine; 3,3',5-Triiodo-L-thyronine; T3)
| Size | Price | Stock |
|---|---|---|
| 100mg | $60 | In-stock |
| 500mg | $130 | In-stock |
| 1g | $208 | In-stock |
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| 10 g | Get quote | |
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| Cat. No. : | HY-A0070A |
| M.Wt: | 650.97 |
| Formula: | C15H12I3NO4 |
| Purity: | >98 % |
| Solubility: | 1M NaOH : 50 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : 50 mg/mL (ultrasonic) |
Liothyronine is an active form of thyroid hormone. Liothyronine binds to thyroid hormone receptors TRα and TRβ with Kis of 2.33 and 2.29 nM for hTRα and hTRβ, respectively. Liothyronine also binds to PVR and blocks the interaction of TIGIT/PVR[1][2][3]. IC50 & Target:TRβ1[1][2] In Vitro: hepatocarcinomaLiothyronine (T3, 100 nM) stimulates the proliferation of hepatocarcinema cells in which TRβ1 is overexpressed[1]. Liothyronine binds to the human β1 thyroid hormone receptor (hTRβ1), and changes its conformation. Liothyronine promotes growth, induces differentiation and regualtes metabolic effects[2].
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