Ceftolozane
CAS No. : 689293-68-3
(Synonyms: CXA-101 (free base); FR264205 (free base))
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| Cat. No. : | HY-19806 |
| M.Wt: | 666.69 |
| Formula: | C23H30N12O8S2 |
| Purity: | >98 % |
| Solubility: | DMSO : 24 mg/mL (ultrasonic;adjust pH to 2 with HCl) |
Ceftolozane (CXA-101 free base; FR264205 free base) is a cephalosporin antibiotic with potent activity againstPseudomonas aeruginosa and strains Enterobacteriaceae, with MICs of 0.5 and 0.25-0.5 mg/L[1]. In Vivo: Ceftolozane (25 mg/kg) reveals a pharmacokinetic profil with a half-time of 11.6 min and a clearance of 25.2 μg/mL in infected neutropenic mice[1].
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