Elubrixin
CAS No. : 688763-64-6
(Synonyms: SB-656933)
| Size | Price | Stock |
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| 5mg | $250 | Get quote |
| 10mg | $390 | Get quote |
| 25mg | $820 | Get quote |
| 50mg | $1300 | Get quote |
| 100mg | $1950 | Get quote |
| 200 mg | Get quote | |
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| Cat. No. : | HY-18263A |
| M.Wt: | 463.31 |
| Formula: | C17H17Cl2FN4O4S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Elubrixin (SB-656933) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation[1][2][3].
IC50 & Target:CXCR2[2][3]
IL-8 receptor[1]
In Vitro:Elubrixin has an inhibitory effect on neutrophils in a dose-dependent fashion[1].
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