SU-11752
CAS No. : 688036-19-3
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| Cat. No. : | HY-114923 |
| M.Wt: | 493.57 |
| Formula: | C26H27N3O5S |
| Purity: | >98 % |
| Solubility: |
SU-11752 is an inhibitor for DNA-dependent protein kinase (DNA-PK) with an IC50 of 0.13 μM. SU-11752 inhibits PI3K p110γ kinase with IC50 of 1.1 μM. SU-11752 binds competitively for ATP-site in DNA-PK, results in inhibition of intracellular DNA double-strand break repair and increases the sensitivity of cells to radiotherapy[1].
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