Dihydrochelerythrine
CAS No. : 6880-91-7
(Synonyms: 12,13-Dihydrochelerythrine)
| Size | Price | Stock |
|---|---|---|
| 5mg | $65 | In-stock |
| 10mg | $100 | In-stock |
| 25mg | $200 | In-stock |
| 50mg | $320 | In-stock |
| 100mg | $512 | In-stock |
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| Cat. No. : | HY-N0903 |
| M.Wt: | 349.38 |
| Formula: | C21H19NO4 |
| Purity: | >98 % |
| Solubility: | DMSO : 20.83 mg/mL (ultrasonic) |
Dihydrochelerythrine is a natural compound isolated from Corydalis yanhusuo; has antifungal activity. IC50 value: Target: in vitro: Dihydrochelerythrine showed the highest antifungal activity against B. cinerea Pers, with 98.32% mycelial growth inhibition at 50 μg/mL. Dihydrochelerythrine inhibited spore germination in vitro in a concentration-dependent manner [1]. Dihydrochelerythrine appeared to be less cytotoxic since the viability of cells exposed to 20 microM dihydrochelerythrine for 24h was reduced only to 53%. A dose-dependent induction of apoptosis and necrosis by chelerythrine and dihydrochelerythrine was confirmed by annexin V/propidium iodide dual staining flow cytometry [2]. Dihydrochelerythrine (4) exhibited strong activity against methicillin-resistant Staphylococcus aureus SK1 and moderate activity against Escherichia coli TISTR 780 with MIC values of 8 and 16 μg/mL, respectively [3].
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