PX-478 (Standard)
CAS No. : 685898-44-6
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| Cat. No. : | HY-10231R |
| M.Wt: | 394.12 |
| Formula: | C13H20Cl4N2O3 |
| Purity: | >98 % |
| Solubility: |
PX-478 (Standard) is the analytical standard of PX-478 (HY-10231). This product is intended for research and analytical applications. PX-478 is a multifunctional HIF-1α inhibitor with properties including radiosensitization, autophagy activation, and lipid accumulation inhibition. PX-478 also blocks hypoxia-induced VEGF production and regulates β-cell phenotypes under hypoxic conditions. PX-478 induces cell cycle arrest and DNA damage, restores autophagic function, reduces foam cell formation, and maintains glucose homeostasis. PX-478 is widely used in research on related diseases such as human tumors (e.g., prostate cancer), type 2 diabetes, and atherosclerosis[1][2][3][4].
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