E-2508 (free base)
CAS No. : 685885-75-0
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| Cat. No. : | HY-119114 |
| M.Wt: | 493.64 |
| Formula: | C29H39N3O4 |
| Purity: | >98 % |
| Solubility: |
E-2508 free base is an orally active and highly selective corticotropin-releasing factor type 1 receptor (CRF1) antagonist with anxiolytic effects (Ki=11 nM). E-2508 free base blocks CRF-induced cAMP accumulation via CRF1 receptor inhibition. E-2508 free base is promising for research of stress-related psychiatric disorders, such as anxiety and depression[1].
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