Mecasermin
CAS No. : 68562-41-4
(Synonyms: Human IGF-I; FK 780)
| Size | Price | Stock |
|---|---|---|
| 1mg | $535 | In-stock |
| 5mg | $1350 | In-stock |
| 10mg | $2160 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-108905 |
| M.Wt: | 7645.68 |
| Formula: | C331H512N94O101S7 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Mecasermin (Human IGF-I; FK 780) is a recombinant human insulin-like growth factor I (IGF-I). Mecasermin has the potential for the study of the growth failure of growth hormone (GH) insensitivity caused by GH receptor defects or GH-inhibiting antibodies[1]. In Vivo: Mecasermin (rhIGF1; 0.25 mg/kg; i.p.; daily; 6 weeks) increases IGF1 concentration in serum to near-normal levels and ameliorates a wide range of phenotypes, including organismal and behavioral function, synaptic and circuit plasticity, neuronal structure, and molecular signaling pathways[2].
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