Disuccinimidyl suberate Crosslinker


CAS No. : 68528-80-3

68528-80-3
Price and Availability of CAS No. : 68528-80-3
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Cat. No. : HY-W019543
M.Wt: 368.34
Formula: C16H20N2O8
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 68528-80-3 :

Disuccinimidyl suberate Crosslinker is an amine-reactive bifunctional protein crosslinker. Disuccinimidyl suberate Crosslinker enables stable protein-protein, peptide, and biomolecule conjugation. In Vitro:NHS esters react with primary amines at pH 7-9 to form stable amide bonds, along with release of the N-hydroxysuccinimide leaving group. Proteins, including antibodies, generally have several primary amines in the side chain of lysine (K) residues and the N-terminus of each polypeptide that are available as targets for NHS-ester crosslinking reagents. Disuccinimidyl suberate Crosslinker is first dissolved in an organic solvent such as DMSO, then added to the aqueous crosslinking reaction.

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