Apyramide


CAS No. : 68483-33-0

68483-33-0
Price and Availability of CAS No. : 68483-33-0
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Cat. No. : HY-U00046
M.Wt: 490.93
Formula: C27H23ClN2O5
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 68483-33-0 :

Apyramide is an anti-inflammatory agent (NSAID) and behaves as a prodrug of indomethacin (HY-14397)[1]. Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2. In Vivo: Apyramide is far less toxic than indomethacin in rats and mice by the oral or the i.p. route. It exhibits anti-inflammatory activity on carrageenin-induced paw oedema, cotton pellet granuloma and adjuvant arthritis, as well as analgesic and antipyretic activities[1].

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