(E/Z)-4-Hydroxytamoxifen (Standard)


CAS No. : 68392-35-8

(Synonyms: Afimoxifene (Standard); 4-OHT (Standard))

68392-35-8
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Cat. No. : HY-16950AR
M.Wt: 387.51
Formula: C26H29NO2
Purity: >98 %
Solubility:
Introduction of 68392-35-8 :

(E/Z)-4-Hydroxytamoxifen (Standard) is the analytical standard of (E/Z)-4-Hydroxytamoxifen. This product is intended for research and analytical applications. (E/Z)-4-Hydroxytamoxifen (Afimoxifene) is a racemic compound of (Z)-4-Hydroxytamoxifen and (E)-4-Hydroxytamoxifen isomers. (E/Z)-4-Hydroxytamoxifen is a selective estrogen receptor modulator with mixed estrogenic and antiestrogenic activity, which is also an active metabolite of Tamoxifen (HY-13757A). (E/Z)-4-Hydroxytamoxifen is an agonist of the G protein-coupled estrogen receptor (GPER) with relatively low affinity (100-1000 nM). (E/Z)-4-Hydroxytamoxifen is promising for research of cyclical mastalgia, such as breast pain, tenderness, and nodularity[1][2][3][4].

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