20-(tert-Butoxy)-20-oxoicosanoic acid
CAS No. : 683239-16-9
| Size | Price | Stock |
|---|---|---|
| 250mg | $7 | In-stock |
| 1g | $15 | In-stock |
| 5g | $49 | In-stock |
| 10g | $90 | In-stock |
| 25g | $169 | In-stock |
| 100g | $657 | In-stock |
| 250g | $1366 | In-stock |
| 500g | $2482 | In-stock |
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| 2 kg | Get quote | |
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| Cat. No. : | HY-W034597 |
| M.Wt: | 398.62 |
| Formula: | C24H46O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 20-(tert-Butoxy)-20-oxoicosanoic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2].
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