2-Bromoacetamide


CAS No. : 683-57-8

683-57-8
Price and Availability of CAS No. : 683-57-8
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Cat. No. : HY-W007330
M.Wt: 137.96
Formula: C2H4BrNO
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 683-57-8 :

2-Bromoacetamide is a disinfection byproduct. 2-Bromoacetamide can inactivate liver alcohol dehydrogenase and interfere with microtubule and actin cytoskeletal function. 2-Bromoacetamide is a potent developmental toxicant in animals[1][2][3]. In Vitro:2-Bromoacetamide inactivates liver alcohol dehydrogenase[1].
2-Bromoacetamide (250 μM-1 mM) reduces the egg cylinder formation rate in a dose-dependent manner, disrupts cell lineage differentiation in mouse embryo[2].
2-Bromoacetamide (3.5-4 mg/L; 8-24 h) reduces the first polar body extrusion rate in a dose-dependent manner, disrupts spindle structure, interferes with microtubule and actin cytoskeleton functions in mouse and human oocyte[3].

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