6,8-Diprenylnaringenin
CAS No. : 68236-11-3
(Synonyms: Lonchocarpol A; Senegalensin)
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| Cat. No. : | HY-122416 |
| M.Wt: | 408.49 |
| Formula: | C25H28O5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
6,8-Diprenylnaringenin (Lonchocarpol A; Senegalensin), a hop prenylflavonoid, is a inhibitor of breast cancer resistance protein (BCRP/ABCG2). 6,8-Diprenylnaringenin inhibits ABCG2-mediated efflux of Mitoxantrone, and 3H-Methotrexate transport (IC50=0.41 μM) in HEK293 cells. 6,8-Diprenylnaringenin exhibits some estrogenicity, but its potency is less than 1% of that of 8-Prenylnaringenin[1][2].
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