A-800141


CAS No. : 681245-85-2

681245-85-2
Price and Availability of CAS No. : 681245-85-2
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Cat. No. : HY-119062
M.Wt: 442.57
Formula: C24H30N2O4S
Purity: >98 %
Solubility:
Introduction of 681245-85-2 :

A-800141 is an orally active and selective MetAP2 inhibitor with an IC50 of 12 nM. A-800141 has weak inhibitory activity for MetAP1 (IC50 : 36 μM). GAPDH can be used as a biomarker to monitor the MetAP2 inhibition of A-800141. A-800141 has antiangiogenic and anticancer activity in a variety of xenograft tumor models[1].

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