| Size | Price | Stock |
|---|---|---|
| 1mg | $80 | In-stock |
| 5mg | $170 | In-stock |
| 10 mg | Get quote | |
| 50 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
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| Cat. No. : | HY-N0834 |
| M.Wt: | 913.10 |
| Formula: | C47H76O17 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 39 mg/mL |
Pulsatilla saponin D (SB365), isolated from the root of Pulsatilla chinensis, is an anti-tumor agent[1][2][3][4].
In Vitro: Pulsatilla saponin D (SB365) shows apoptotic effect accompanied by increased evidence of cleaved caspase-3 and poly (ADP ribose) polymerase[1].
Pulsatilla saponin D (SB365) strongly inhibits c-Met expression in gastric cancer cells[1].
Pulsatilla saponin D (SB365) strongly suppresses the growth and proliferation of 5 human pancreatic cancer cell lines (MIAPaCa-2, BXPC-3, PANC-1, AsPC-1 and HPAC) [2].
Pulsatilla saponin D (SB365) shows anti-angiogenic activity by decreasing the expression of HIF-1α and VEGF[3].
Pulsatilla saponin D (0.3 ng/mL to 10 μg/mL) exhibits anti-tumor activity in NSCLC cancer cells[4].
In Vivo: Pulsatilla saponin D (6.4 mg/kg) exhibits anti-tumor activity in Lewis lung carcinoma model[4].
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