SM-324405
CAS No. : 677773-91-0
| Size | Price | Stock |
|---|---|---|
| 5mg | $145 | In-stock |
| 10mg | $230 | In-stock |
| 25mg | $430 | In-stock |
| 50mg | $680 | In-stock |
| 100mg | $1050 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-110207 |
| M.Wt: | 385.42 |
| Formula: | C19H23N5O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic) |
SM-324405 is a TLR7 agonistic antedrug (EC50 = 50 nM), with pEC50 values of 7.3 and 6.6 for human TLR7 and Rat TLR7, respectively. SM-324405 is used for immunotherapy of allergic diseases. An antedrug is defined as a locally active compound that is designed to be rapidly metabolized to an inactive form upon entry into the circulation and prevents systemic toxicity by losing its agonistic activity in a plasmatic environment[1][2][3].
In Vitro: SM-324405 is a novel candidate for immunotherapy of allergic diseases[1].
In Vivo: SM-324405 (9e, intratracheal administration) effectively inhibits allergen-induced airway inflammation without inducing cytokines systemically[1].
SM-324405 is metabolized to the corresponding acid in human plasma with t1/2 of 2.6 min[1][2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- SM-324405
- Cat. No.:
- HY-110207
- Quantity:
Your information is safe with us.