S-Nitroso-N-acetyl-DL-penicillamine


CAS No. : 67776-06-1

(Synonyms: SNAP)

67776-06-1
Price and Availability of CAS No. : 67776-06-1
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50mg $32 In-stock
100mg $53 In-stock
250mg $63 In-stock
1g $208 In-stock
5g $868 In-stock
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Cat. No. : HY-121526
M.Wt: 220.25
Formula: C7H12N2O4S
Purity: >98 %
Solubility: DMSO : 250 mg/mL (ultrasonic);H2O : 11.11 mg/mL (ultrasonic)
Introduction of 67776-06-1 :

S-Nitroso-N-acetyl-DL-penicillamine (SNAP) is a nitric oxide donor and acts as a stable inhibitor of platelet aggregation[1][2][3][4]. In Vitro: S-Nitroso-N-acetyl-DL-penicillamine (10 mM; 8 hours) induces toxicity of about 80% after 6 hours under normoxic conditions by releasing nitric oxide (NO)[1].
S-Nitroso-N-acetyl-DL-penicillamine has a half-time about 6 hours in in isolated rat ventricular myocytes[3].
S-Nitroso-N-acetyl-DL-penicillamine (100 µM; 30 minutes) causes sustained decrease in the basal pHi in isolated rat ventricular myocytes[3].
In Vivo: SNAP (100μM, 300μM) causes small but significant increases of the electrically evoked [3H]-acetylcholine release in guinea-pig tracheal[4].

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