3-Hydroxyflunitrazepam
CAS No. : 67739-71-3
(Synonyms: 3-OH FNTZ)
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| Cat. No. : | HY-121057 |
| M.Wt: | 329.28 |
| Formula: | C16H12FN3O4 |
| Purity: | >98 % |
| Solubility: |
3-Hydroxyflunitrazepam (3-OH FNTZ) is the major metabolite of Flunitrazepam (FNTZ), generated via 3-hydroxylation by CYP3A4 (Km = 286 μM), and represents the dominant metabolic pathway (>80%) in liver microsomes. Its formation is significantly inhibited by CYP3A4 inhibitors such as Ketoconazole (HY-B0105) (IC50 = 0.11 μM) and Ritonavir (HY-90001) (IC50 = 0.041 μM), indicating a strong dependence on CYP3A4 activity and potential drug interactions[1].
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- 3-Hydroxyflunitrazepam
- Cat. No.:
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