Facinicline


CAS No. : 677306-35-3

(Synonyms: RG3487 (free base))

677306-35-3
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Cat. No. : HY-108057
M.Wt: 270.33
Formula: C15H18N4O
Purity: >98 %
Solubility:
Introduction of 677306-35-3 :

Facinicline (RG3487) is an orally active nicotinic α7 receptor partial agonist, with a Ki of 6 nM for α7 human nAChR. Facinicline improves cognition and sensorimotor gating in rodents. Facinicline hydrochloride shows high affinity (antagonist) to 5-HT3Rs with a Ki value of 1.2 nM[1].

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