N-Butanoyl-L-homoserine lactone


CAS No. : 67605-85-0

(Synonyms: C4-HSL; N-Butyryl-L-homoserine lactone)

67605-85-0
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Cat. No. : HY-114816
M.Wt: 171.20
Formula: C8H13NO3
Purity: >98 %
Solubility: H2O : 20 mg/mL (ultrasonic;warming;heat to 60°C);DMSO : 100 mg/mL (ultrasonic)
Introduction of 67605-85-0 :

N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1]. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa[2][3]. In Vitro: The dissociation constant (Kd value) of aptamer binding to N-Butanoyl-L-homoserine lactone (C4-HSL) is 28.47 nM[2].

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