VO-OHPic


CAS No. : 675848-25-6

675848-25-6
Price and Availability of CAS No. : 675848-25-6
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Cat. No. : HY-110067
M.Wt: 361.16
Formula: C12H10N2O8V
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 675848-25-6 :

VO-OHPic is a reversible, noncompetitive and selective PTEN inhibitor with an IC50 of 46 nM. VO-OHPic attenuates apoptosis, adverse cardiac remodeling, and pro-inflammatory M1 macrophages in doxorubicin-induced cardiomyopathy. VO-OHPic inhibits autophagy[1][2][3]. IC50 & Target: IC50: 46 nM (PTEN)[1]

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