Pralidoxime
CAS No. : 6735-59-7
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| Cat. No. : | HY-B1738 |
| M.Wt: | 137.16 |
| Formula: | C7H9N2O+ |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Pralidoxime is a potent reactivator of acetylcholinesterase (AChE). Pralidoxime reactivates nerve agent-inhibited AChE via direct nucleophilic attack by the oxime moiety on the phosphorus center of the bound nerve agent. Pralidoxime is an antidote for organophosphate poisoning[1][2]. In Vivo: Pralidoxime (10-150 mg/kg; intramuscular administration, once) reverses paraoxon-induced respiratory toxicity in mice[3].
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