5-Hydroxymethylfurfural


CAS No. : 67-47-0

(Synonyms: 2-Hydroxymethyl-5-furfural; 2-Formyl-5-hydroxymethylfuran)

67-47-0
Price and Availability of CAS No. : 67-47-0
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Cat. No. : HY-Y0051
M.Wt: 126.11
Formula: C6H6O3
Purity: >98 %
Solubility: DMSO : ≥ 50 mg/mL
Introduction of 67-47-0 :

5-Hydroxymethylfurfural (2-Hydroxymethyl-5-furfural), derived from Cornus officinalis, inhibits yeast growth and fermentation as stressors. IC50 & Target:Yeast[1]. In Vitro: It is found that furfural and HMF cause the attenuation of bulk translation activity and the assembly of cytoplasmic mRNP granules in Saccharomyces cerevisiae. Notably, a combination of furfural and HMF induce the remarkable repression of translation initiation and SG formation. Furfural and HMF can induce the formation of cytoplasmic mRNP granules, HMF also causes a gradual reduction in the polysome fraction and a concomitant increase in the 80S monosome fraction[1].

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