Nitrofurantoin
CAS No. : 67-20-9
| Size | Price | Stock |
|---|---|---|
| 5g | $14 | In-stock |
| 10g | $25 | In-stock |
| 25g | $39 | In-stock |
| 100g | $48 | In-stock |
| 500g | $171 | In-stock |
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| Cat. No. : | HY-A0090 |
| M.Wt: | 238.16 |
| Formula: | C8H6N4O5 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Nitrofurantoin is a potent and orally active broad-spectrum beta-lactamase antimicrobial agent. Nitrofurantoin acts as an antibiotic and can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections[1]. In Vitro:Nitrofurantoin (0-512 mg/L; 8 h) treatment inhibits the growth of E. coli isolates[3]. In Vivo:
| Parameters | 10 mg/kg p.o. | 2 mg/kg i.v. |
| AUC0-720 (μg/mL·min) | 306 | |
| AUC0-120 (μg/mL·min) | 90.3 | |
| AUC0-∞ (μg/mL·min) | 344 | 91.5 |
| Cmax (μg/mL) | 1.01 | |
| CL/F or CL (ml/min/kg) | 31.0 | 22.7 |
| t1/2 (min) | 166 | 23.6 |
| Bioavailability (%) | 60.1 | |
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