Encainide (hydrochloride)
CAS No. : 66794-74-9
(Synonyms: MJ9067 (hydrochloride))
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| Cat. No. : | HY-12531 |
| M.Wt: | 388.93 |
| Formula: | C22H29ClN2O2 |
| Purity: | >98 % |
| Solubility: | H2O : 1000 mg/mL (ultrasonic;warming;heat to 80°C) |
Encainide (MJ9067) hydrochloride is an antiarrhythmic agent with class IC activity. Encainide hydrochloride blocks voltage-dependent potassium channels. Encainide hydrochloride has the potential for life-threatening ventricular arrhythmias, symptomatic ventricular arrhythmias and supraventricular arrhythmias research[1][2]. In Vivo:Encainide hydrochloride (MJ9067 hydrochloride; 0.3, 0.9, 2.7 mg/kg; infusion of single doses) prolongs His-Purkinje conduction time (HV interval) and intra-ventricular conduction time (QRS duration) but has no effect on sinus nodal recovery time or AV nodal conduction, or on refractoriness of atrium, AV node, or ventricular myocardium or on QT interval[1].
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