TS-021
CAS No. : 667865-69-2
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| Cat. No. : | HY-U00346A |
| M.Wt: | 401.45 |
| Formula: | C17H24FN3O5S |
| Purity: | >98 % |
| Solubility: |
TS-021 is a selective, orally active, reversible and long-acting DPP-IV inhibitor, and exhibits significant inhibition selectivity against DPP-8 (> 600 fold), DPP-9 (> 1200 fold) and other peptidases (> 15,000 fold). TS-021 inhibits DPP-IV activity in human plasma with an IC50 value of 5.34 nM. TS-021 has long-term persistent plasma drug concentration and potent antihyperglycemic activity, and increases in the active form of GLP-1[1][2].
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