MeBIO
CAS No. : 667463-95-8
| Size | Price | Stock |
|---|---|---|
| 5mg | $85 | In-stock |
| 10mg | $145 | In-stock |
| 25mg | $280 | In-stock |
| 50mg | $450 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
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| Cat. No. : | HY-103221 |
| M.Wt: | 370.20 |
| Formula: | C17H12BrN3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 14.71 mg/mL (ultrasonic;warming;heat to 60°C) |
MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist, with IC50 of 44 μM (GSK-3) and 55 μM (CDK1/cyclin B), respectively[1]. IC50 & Target:IC50: 44 μM (GSK-3), 55 μM (CDK1/cyclin B), >100 μM (CDK5/p25)[1] In Vitro:MeBIO (25 μM, 90 min) causes redistribution of AhR to the nucleus in wild-type Hepa-1 and ARNT mutant cells[2]. MeBIO (10 μM, 24 h) induces the aggregation of 5L cells in the G1 phase and increases the upregulation of p27 KIP1 expression in 5L cells[2].
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