PG-931
CAS No. : 667430-81-1
| Size | Price | Stock |
|---|---|---|
| 1mg | $75 | In-stock |
| 5mg | $188 | In-stock |
| 10mg | $300 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-P1208 |
| M.Wt: | 1180.40 |
| Formula: | C59H85N15O11 |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic) |
PG-931, an analog of SHU 9119 (HY-P0227), is a potent melanocortin 4 (MC4) receptor (IC50=0.58 nM) agonist and is more selective than for the hMC3R (IC50=55 nM) or the hMC5R (IC50=2.4 nM). PG-931 can reverse haemorrhagic shock and prevent multiple organ damage in vivo[2]. IC50 & Target:IC50: 0.58 nM (melanocortin 4 receptor)IC50: 2.4 nM (melanocortin 5 receptor)IC50: 55 nM (melanocortin 3 receptor)[1] In Vivo: PG-931 (intravenous?injection; 13-108 nmol/kg; single dose) produces a dose-dependent restoration of cardiovascular and respiratory functions, and improved survival in Wistar rats with haemorrhagic shock[2].
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