Mizagliflozin
CAS No. : 666843-10-3
(Synonyms: DSP-3235 (free base); KGA-3235 (free base); GSK-1614235 (free base))
| Size | Price | Stock |
|---|---|---|
| 5mg | $180 | In-stock |
| 10mg | $290 | In-stock |
| 25mg | $580 | In-stock |
| 50mg | $820 | In-stock |
| 100mg | $1200 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-17638 |
| M.Wt: | 564.67 |
| Formula: | C28H44N4O8 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic);H2O : ≥ 100 mg/mL |
Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic drug that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation[1].
IC50 & Target: Ki: 27 nM (hSGLT1), 8170 nM (hSGLT2)[1]
In Vivo: Mizagliflozin (DSP-3235 free base) (3-30 mg/kg; oral) exerts a laxative effect[1].
Mizagliflozin administrated intravenously (0.3?mg/kg) and orally (3?mg/kg) declined with a short half-life (0.23 and 1.14?h, respectively)[2]
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Mizagliflozin
- Cat. No.:
- HY-17638
- Quantity:
Your information is safe with us.