4',5-Dihydroxyflavone
CAS No. : 6665-67-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $45 | In-stock |
| 10mg | $70 | In-stock |
| 25mg | $140 | In-stock |
| 50mg | $224 | In-stock |
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| 200 mg | Get quote | |
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| Cat. No. : | HY-N1881 |
| M.Wt: | 254.24 |
| Formula: | C15H10O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
4',5-Dihydroxyflavone (Compound 2c; Compound B3) is a type of flavonoid compound. 4',5-Dihydroxyflavone can inhibit various oxidases and its IC50 values for collagenase A (ColA) and α-glucosidase are less than 1 μM and 66 μM respectively; for soybean lipoxygenase-1 (LOX-1), its Ki value is 102.6 μM. 4',5-Dihydroxyflavone can be used in studies on anti-toxicity and anti-diabetes[1][2][3].
IC50 & Target:Ki: 102.6 μM (LOX-1)[1].
IC50: 66 μM (α-glucosidase)[2].
In Vitro:4',5-Dihydroxyflavone is a potent inhibitor of ColA, which is a crucial bacterial virulence factor. It helps bacteria spread by degrading host collagen proteins[3].
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