Fosmidomycin sodium salt
CAS No. : 66508-37-0
(Synonyms: FR-31564)
| Size | Price | Stock |
|---|---|---|
| 5mg | $220 | In-stock |
| 10mg | $352 | In-stock |
| 25mg | $635 | In-stock |
| 50mg | $1016 | In-stock |
| 100mg | $1625 | In-stock |
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| Cat. No. : | HY-112853 |
| M.Wt: | 205.08 |
| Formula: | C4H9NNaO5P |
| Purity: | >98 % |
| Solubility: | H2O : 25 mg/mL (ultrasonic;warming;heat to 60°C) |
Fosmidomycin sodium salt is a phosphonic acid antibiotic and a antimalarial agent, which is active against both Gram-negative and Gram-positive bacteria. In Vitro: Fosmidomycin sodium salt is a phosphonic acid antibiotic[1][2], which is active against both Gram-negative and Gram-positive bacteria[3]. In Vivo: Animals treated intraperitoneally with dosages of >10 mg/kg of fosmidomycin are apparently free of parasites. After treatment with 5 mg/kg of fosmidomycin, parasitemias are <1%. Animals treated orally with 50 or 100 mg/kg of fosmidomycin are apparently free of parasites, and parasitemias are <1% after treatment with 20 mg/kg of drug. Recrudescence is observed when the treatment is terminated after 4 days. Mice treated with 30 mg/kg of fosmidomycin over a period of 8 days are totally cured[3].
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