DOV-216,303 (Free Base)
CAS No. : 66504-40-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $75 | In-stock |
| 10mg | $120 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-18332C |
| M.Wt: | 228.12 |
| Formula: | C11H11Cl2N |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 125 mg/mL;Ethanol : 100 mg/mL (ultrasonic) |
DOV-216,303 (Free Base) is a potent triple serotonin, norepinephrine, and dopamine reuptake inhibitor, with IC50 values of 14 nM, 20 nM and 78 nM for hSERT, hNET and hDAT, respectively. Has antidepressant-like effects and increases monoamine release in the prefrontal cortex of olfactory bulbectomized (OBX) rats[1][2]. IC50 & Target:IC50: 14 nM (serotonin), 20 nM (norepinephrine), 78 nM (dopamine)[1].
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