Arterolane


CAS No. : 664338-39-0

(Synonyms: OZ 277; RBx 11160)

664338-39-0
Price and Availability of CAS No. : 664338-39-0
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Cat. No. : HY-10852
M.Wt: 392.53
Formula: C22H36N2O4
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 664338-39-0 :

Arterolane is an antimalarial agent, with IC50 of both 1.1 nM against P. falciparum Ro73 and W2, respectively. IC50 & Target: IC50: 1.1 nM (P. falciparum Ro73), 1.1 nM (P. falciparum W2)[1] In Vitro: Arterolane (Trioxolane 7; OZ277; RBx-11160) is an antimalarial agent, with IC50s of both 1.1 nM (0.43 ng/mL) against P. falciparum Ro73 and W2, respectively. Arterolane also shows inhibitory activity against several other P. falciparums, with IC50s of 1.0, 1.6, 0.90, 0.91, 1.4, 1.5, 0.83, and 0.84 ng/mL for P. falciparum K1, Fc27, FVO, NF54, HB3, FCB1, ITG2-F6, and MAD20, respectively[1].

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