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|---|---|---|
| 100 mg | Get quote | |
| 250 mg | Get quote | |
| 500 mg | Get quote | |
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Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-N3950 |
| M.Wt: | 442.72 |
| Formula: | C30H50O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Glochidiol is an orally active tubulin polymerization inhibitor with an IC50 of 2.76 μM. Glochidiol shows anti-cancer activity[1].
IC50 & Target:IC50: 2.76 μΜ (tubulin polymerization)[1]
In Vitro:Glochidiol (1-8 μM; 48 h) shows potent antiproliferative activity against lung cancer cell lines in a concentration-dependent manner[1].
Glochidiol interacts with tubulin by targeting the colchicine binding site[1].
In Vivo:Glochidiol (60 mg/kg/day; i.g.; 21 days) effectively inhibits lung cancer HCC-44 xenograft tumor growth in nude mice[1].
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