Glochidiol


CAS No. : 6610-56-6

6610-56-6
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Cat. No. : HY-N3950
M.Wt: 442.72
Formula: C30H50O2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 6610-56-6 :

Glochidiol is an orally active tubulin polymerization inhibitor with an IC50 of 2.76 μM. Glochidiol shows anti-cancer activity[1]. IC50 & Target:IC50: 2.76 μΜ (tubulin polymerization)[1] In Vitro:Glochidiol (1-8 μM; 48 h) shows potent antiproliferative activity against lung cancer cell lines in a concentration-dependent manner[1].
Glochidiol interacts with tubulin by targeting the colchicine binding site[1]. In Vivo:Glochidiol (60 mg/kg/day; i.g.; 21 days) effectively inhibits lung cancer HCC-44 xenograft tumor growth in nude mice[1].

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