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Arachidonic acid (sodium salt)


CAS No. : 6610-25-9

(Synonyms: Immunocytophyt (sodium salt))

6610-25-9
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Cat. No. : HY-109590A
M.Wt: 326.45
Formula: C20H31NaO2
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 6610-25-9 :

Arachidonic acid (Immunocytophyt) sodium salt is a polyunsaturated omega-6 fatty acid and a major constituent of biomembranes. Arachidonic acid sodium salt also acts as the substrate for various lipid mediators, such as prostaglandins (PGs). Arachidonic acid sodium salt improves cognitive response and cardiovascular function[1]. In Vivo:Arachidonic acid sodium salt can be used to induce paw edema models[2].

Induction of Paw Edema Model[2]
Background
Principle: Injecting arachidonic acid into the hind paws of rats can induce rapid and sustained inflammatory responses.
Specific Mmodeling Methods
Rat: Lewis • male •
Administration: 0.5% • s.c. • single dose
Note
A single subcutaneous injection of 0.10 mL of arachidonic acid (dissolved in 0.2 M carbonate buffer with a pH value of 8.43-8.56) was administered into the right hind paw of male Lewis rats weighing 144-241 grams.
Modeling Indicators
Appearance Monitoring: Significant edema became apparent within 5 minutes, and the reaction reached its peak at 1 hour after injection.
Correlated Product(s): /
Opposite Product(s): phenidone (HY-W010144); SK&F86002 (HY-12511)

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